Correlation of morbidity and mortality from Malignant Neoplasms of the Gastrointestinal Tract in the population of Curimataú Paraibano Ocidental

Authors

  • Adyverson Gomes dos Santos Universidade Federal de Campina Grande
  • Girleide Santos do Nascimento Federal University of Campina Grande
  • Bruna Braga Dantas Federal University of Campina Grande

DOI:

https://doi.org/10.48017/dj.v7i4.2380

Keywords:

Basic health indicators, Gastric neoplasms, Statistics, Demographics

Abstract

The health indicators - morbidity and mortality - from cancer point to an exponential growth, configuring a public health problem that must be investigated. The objective was to identify and correlate the morbidity and mortality of Malignant Neoplasms of the Gastrointestinal Tract in a microregion of Curimatau, Paraíbano Ocidental. A documentary research was carried out with sampling of a microregion of Curimatau Paraíbano Ocidental, using DataSUS, with the research divided into three stages: collection of sociodemographic data, stratification of morbidity and mortality by NMTGI and analysis of the correlation coefficient according to Pearson. When observing the demographic censuses, it is clear that there was a population growth and as this occurs, the per capita income increases, while the percentage of people with low income decreases, equivalent to a negative correlation (-0.994). Regarding morbidity and mortality from NMTGI, the definitions of neoplasms show convergent evolutions, represented by positive correlations (≥0.80; p<0.01), on the other hand, when the morbidity and mortality of different cancers are correlated from the TGI, negative correlations are observed (≥-0.80; p>0.05), however both correlations show a shared variance of up to 83% between the NMs. Thus, it is speculated that there are predisposing factors such as risk, environmental, genetic or social factors that contribute to the emergence of MN, requiring in-depth research on these causal factors.

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Author Biography

Bruna Braga Dantas, Federal University of Campina Grande

She holds a bachelor's degree in Nursing from the Federal University of Paraíba (2011), a specialist in Public Health from the Integrated Faculty of Patos (2011), a master's degree in Pharmacology of Bioactive Natural and Synthetic Products (2014) and a PhD in Biotechnology - RENORBIO (2018), both from the Federal University of Paraiba. He has research experience in the field of cellular and molecular pharmacology, with an emphasis on evaluating the cytotoxic and anticancer activity of natural and synthetic molecules. She is currently an Adjunct Professor at the Academic Health Unit of the Federal University of Campina Grande - Campus Cuité and coordinator of the OCC (Curimataú Cancer Observatory), a study center for the development and guidance of related research, teaching and extension projects, especially , oncology and health promotion.

References

Alves de Oliveira, V., Nogueira de Oliveira, T. W., Barros de Alencar, M. V. O., Santos Cerqueira, G., Paula Peron, A., & De Castro e Sousa, J. M. (2015). Relação entre consumo alimentar da população nordestina e o alto índice de câncer gástrico nesta região. Revista Intertox de Toxicologia, Risco Ambiental e Sociedade, 7(3), 6–24. https://doi.org/10.22280/revintervol7ed3.181

Antonio, J. (2019). Polimorfismos genéticos e o câncer de cavidade oral e laringe : contribuição do álcool e fumo São Paulo Polimorfismos genéticos e o câncer de cavidade oral e laringe: contribuição do álcool e fumo São Paulo. Universidade de São Paulo USP.

Arruda, N. M., Maia, A. G., & Alves, L. C. (2018). Inequality in access to health services between urban and rural areas in Brazil: A disaggregation of factors from 1998 to 2008. Cadernos de Saude Publica, 34(6), 1–14. https://doi.org/10.1590/0102-311X00213816

Baptista, E. A., Queiroz, B. L., & Pinheiro, P. C. (2021). Regional Distribution of Causes of Death for Small Areas in Brazil, 1998–2017. Frontiers in Public Health, 9(April), 1–12. https://doi.org/10.3389/fpubh.2021.601980

Barbosa, I. R., De Souza, D. L. B., Bernal, M. M., & Do C.c. Costa, Í. (2015). Cancer mortality in Brazil: Temporal trends and predictions for the year 2030. Medicine (United States), 94(16), 1–6. https://doi.org/10.1097/MD.0000000000000746

Bezerra, N. V. F., Leite, K. L. de F., de Medeiros, M. M. D., Martins, M. L., Cardoso, A. M. R., Alves, P. M., Padilha, W. W. N. C., & Cavalcanti, Y. W. (2018). Impact of the anatomical location, alcoholism and smoking on the prevalence of advanced oral cancer in Brazil. Medicina Oral Patologia Oral y Cirugia Bucal, 23(3), e295–e301. https://doi.org/10.4317/medoral.22318

Bigoni, A., Ferreira Antunes, J. L., Weiderpass, E., & Kjærheim, K. (2019). Describing mortality trends for major cancer sites in 133 intermediate regions of Brazil and an ecological study of its causes. BMC Cancer, 19(1), 1–10. https://doi.org/10.1186/s12885-019-6184-1

Bray, F., Ferlay, J., Soerjomataram, I., Siegel, R. L., Torre, L. A., & Jemal, A. (2018). Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 68(6), 394–424. https://doi.org/10.3322/caac.21492

Borges, C. A., Claro, Rafael, M., Martins, A. P. B., Villar, B. S. (2015). Quanto custa para as famílias de baixa renda obterem uma dieta saudável no Brasil?. Cadernos de Saude Publica, 31(1), 137-148. http://dx.doi.org/10.1590/0102-311X00005114

Connell, L. C., Mota, J. M., Braghiroli, M. I., & Hoff, P. M. (2017). The Rising Incidence of Younger Patients With Colorectal Cancer: Questions About Screening, Biology, and Treatment. Current Treatment Options in Oncology, 18(4). https://doi.org/10.1007/s11864-017-0463-3

Cunha, A. R. da, Prass, T. S., & Hugo, F. N. (2019). Mortality from oral and oropharyngeal cancer in Brazil: impact of the National Oral Health Policy. Cadernos de Saude Publica, 35(12), e00014319. https://doi.org/10.1590/0102-311X00014319

Dias, A. de A., Helmer, J. L., Azevedo, S. K. B. C. de, Caldato, C., Oliveira, C. M. de, Moreira, R. C., Dendasck, C. V., & Oliveira, E. de. (2016). Fatores de risco genético e ambientais para o câncer gástrico. Revista Científica Multidisciplinar Núcleo Do Conhecimento, 10(11), 63–72. https://doi.org/10.32749/nucleodoconhecimento.com.br/saude/cancer-gastrico

Dominguez, R. G. S., & Bierrenbach, A. L. (2020). Hospital morbidity and colorectal cancer mortality: Implications for public health in brazil. Arquivos de Gastroenterologia, 57(2), 182–187. https://doi.org/10.1590/s0004-2803.202000000-34

dos Santos, J., Meira, K. C., Simões, T. C., Guimarães, R. M., Telles, M. W. P., Borges, L. F., de Assis, A. C. P., das Vitorias Silva, M., Barbosa, I. R., de Souza Giusti, A. C. B., dos Santos, C. A., & de Souza, D. L. B. (2018). Inequalities in esophageal cancer mortality in Brazil: Temporal trends and projections. PLoS ONE, 13(3), 1–20. https://doi.org/10.1371/journal.pone.0193135

IBGE, I. B. de G. e E. (2021). Portal Cidades. Homepage Na Interntet. https://doi.org/ISSN 0101-4234

INCA, I. N. de C. (2006). A situação do câncer no Brasil. In Ações De Enfermagem Para O Controle Do Câncer.

INCA, I. N. de C. (2020). Estimativa 2020 Incidência de Câncer no Brasil.

Koo, D. H., Han, K. Do, Kim, H. J., & Park, C. Y. (2020). Middle-aged men with type 2 diabetes as potential candidates for pancreatic cancer screening: a 10-year nationwide population-based cohort study. Acta Diabetologica, 57(2), 197–202. https://doi.org/10.1007/s00592-019-01405-7

Magnabosco, P., Oliveira, E. M. de, Toneti, A. N., Anjos, A. C. Y. dos, & Marchi-Alves, L. M. (2017). Prevalence and Control of Hypertension: Comparison Between Urban and Rural Population. REME: Revista Mineira de Enfermagem, 21, 1–8. https://doi.org/10.5935/1415-2762.20170009

Malta, D. C., Moura, L. de, Prado, R. R. do, Escalante, J. C., Schmidt, M. I., & Duncan, B. B. (2014). Mortalidade por doenças crônicas não transmissíveis no Brasil e suas regiões, 2000 a 2011. Epidemiologia e Serviços de Saúde, 23(4), 599–608. https://doi.org/10.5123/s1679-49742014000400002

Melo, A. P. S., França, E. B., Malta, D. C., Garcia, L. P., Mooney, M., & Naghavi, M. (2017). Mortalidade por cirrose, câncer hepático e transtornos devidos ao uso de álcool: Carga Global de Doenças no Brasil, 1990 e 2015. Revista Brasileira de Epidemiologia, 20(1), 61–74. https://doi.org/10.1590/1980-5497201700050006

MINISTÉRIO DA SAÚDE. (2007). Morbidade Hospitalar do SUS por local de internação – de 1984 a 2007 Notas Técnicas Origem dos dados Descrição das variáveis disponíveis para tabulação.

Musia, K., & Zwolińska, D. (2011). Matrix metalloproteinases and soluble Fas/FasL system as novel regulators of apoptosis in children and young adults on chronic dialysis. Apoptosis, 16(7), 653–659. https://doi.org/10.1007/s10495-011-0604-2

Namazi, A., Forat-Yazdi, M., Jafari, M., Farahnak, S., Nasiri, R., Foroughi, E., Abolbaghaei, S. M., & Neamatzadeh, H. (2018). Association of Interleukin-10 -1082 a/G (Rs1800896) Polymorphism With Susceptibility To Gastric Cancer: Meta-Analysis of 6,101 Cases and 8,557 Controls. Arquivos de Gastroenterologia, 55(1), 33–40. https://doi.org/10.1590/s0004-2803.201800000-18

Paranhos, R., Figueiredo Filho, D. B., Rocha, E. C. da, Silva Júnior, J. A. Da, Neves, J. A. B., & Santos, M. L. W. D. (2014). Desvendando os Mistérios do Coeficiente de Correlação de Pearson: o Retorno. Leviathan (São Paulo), 8, 66. https://doi.org/10.11606/issn.2237-4485.lev.2014.132346

Paternoster, S., & Falasca, M. (2020). The intricate relationship between diabetes, obesity and pancreatic cancer. Biochimica et Biophysica Acta - Reviews on Cancer, 1873(1), 188326. https://doi.org/10.1016/j.bbcan.2019.188326

Ruivo, E. A. B., Mello, J. R. C., Cavenaghi, O. M., & Ferreira, L. L. (2018). Perfil sociodemográfico e clínico de pacientes com neoplasia de esôfago e estômago em um hospital escola de São José do Rio Preto, SP. Revista Da Faculdade de Ciências Médicas de Sorocaba, 19(4), 189. https://doi.org/10.23925/1984-4840.2017v19i4a6

Sá-Silva, J. R., Almeida, C. D., & Guindani, J. F. (2009). Pesquisa documental: pistas teóricas e metodológicas. Revista Brasileira de História & Ciências Sociais, 1(1), 1-15.

Valle, T. D., Turrini, R. N. T., & De Brito Poveda, V. (2017). Intervening factors for the initiation of treatment of patients with stomach and colorectal cancer. Revista Latino-Americana de Enfermagem, 25. https://doi.org/10.1590/1518-8345.1493.2879

Published

2022-10-10

How to Cite

Santos, A. G. dos, Nascimento, G. S. do, & Dantas, B. B. (2022). Correlation of morbidity and mortality from Malignant Neoplasms of the Gastrointestinal Tract in the population of Curimataú Paraibano Ocidental. Diversitas Journal, 7(4). https://doi.org/10.48017/dj.v7i4.2380