Development of a Machine Learning based model for early screening for oral cancer

Authors

  • Ivisson Alexandre Pereira da Silva Cesmac University Center
  • Catarina Rodrigues Rosa de Oliveira Cesmac University Center
  • José Marcos dos Santos Oliveira Cesmac University Center
  • Carlos Alberto Correia Lessa Filho Cesmac University Center
  • Sonia Maria Soares Ferreira Cesmac University Center

DOI:

https://doi.org/10.48017/dj.v8i3.2532

Keywords:

Oral cancer, Artificial intelligence, Machine learning

Abstract

Oral Squamous Cell Carcinoma (OSCC) is the most frequent type of oral cancer, accounting for about 40% of malignant head and neck lesions. It ́s known that the favorable prognosis is associated with early diagnosis, since the survival rate increases as a function of the diagnosis in the early stages of the disease. Thus, the objective of this work was to implement and train a Machine Learning model that can help in the diagnosis of oral cancer. Through technologies such as artificial intelligence (AI) that can use images in their analyses, it ́s sought to improve the prognosis of oral cancer through its early detection. Using the branch of AI, Machine Learning and its subgroup Deep Learning, it becomes possible through Convolutional Neural Network (CNN) to perform an image screening of malignant and premalignant lesions, in order to identify the presence or not of oral cancer. The RNC structure is based on the MobileNet structure, which separates the images into fragments and after training, showed the identification of cancer in 91% of the images examined and of Leukoplakia in 84% of the analyzed images.

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Author Biographies

Ivisson Alexandre Pereira da Silva, Cesmac University Center

Student, researcher and master's student of the Professional Master's Degree in Health Research, in Cesmac University Center.

Catarina Rodrigues Rosa de Oliveira, Cesmac University Center

Teacher, Master in Stomatology and Radiology by São Leopoldo Mandic, teacher in the discipline of Clinical Propedeutics in Cesmac University Center.

José Marcos dos Santos Oliveira, Cesmac University Center

Teacher, PhD in Biochemistry and Biotechnology in Cesmac University Center, teacher at the Institute of Chemistry and Biotechnology at and Federal University of Alagoas and of Pharmacy at Cesmac University Center.

Carlos Alberto Correia Lessa Filho, Cesmac University Center

Teacher, researcher, specialist in software development and teacher of Artificial Intelligence discipline in Cesmac University Center.

Sonia Maria Soares Ferreira, Cesmac University Center

Teacher, researcher, coordinator of the Professional Master's Degree in Health Research, in Cesmac University Center.

References

Al-Rawi, N., Sultan, A., Rajai, B., Shuaeeb, H., Alnajjar, M., Alketbi, M., Mohammad, Y., Shetty, S. R., & Mashrah, M. A. (2022). The Effectiveness of Artificial Intelligence in Detection of Oral Cancer: AI AND ORAL CANCER DIAGNOSIS. In International Dental Journal(Vol. 72, pp. 436–447). Elsevier Inc. https://doi.org/10.1016/j.identj.2022.03.001

Aubreville, M., Knipfer, C., Oetter, N., Jaremenko, C., Rodner, E., Denzler, J., Bohr, C., Neumann, H., Stelzle, F., & Maier, A. (2017). Automatic Classification of Cancerous Tissue in Laserendomicroscopy Images of the Oral Cavity using Deep Learning. Scientific Reports, 7(1). https://doi.org/10.1038/s41598-017-12320-8

Erickson, B. J., Korfiatis, P., Akkus, Z., & Kline, T. L. (2017). Machine learning for medical imaging. Radiographics, 37(2), 505-515.

Hurwitz, J., Morris, H., Sidner, C., & Kirsch, D. (2019). Augmented intelligence: the business power of human–machine collaboration. CRC Press.

Ilhan, B., Guneri, P., & Wilder-Smith, P. (2021). The contribution of artificial intelligence to reducing the diagnostic delay in oral cancer. In Oral Oncology (Vol. 116). Elsevier Ltd. https://doi.org/10.1016/j.oraloncology.2021.105254

Ilhan, B., Lin, K., Guneri, P., & Wilder-Smith, P. (2020). Improving Oral Cancer Outcomes with Imaging and Artificial Intelligence. Journal of Dental Research, 99(3), 241–248. https://doi.org/10.1177/0022034520902128

Lin, H., Chen, H., Weng, L., Shao, J., & Lin, J. (2021). Automatic detection of oral cancer in smartphone-based images using deep learning for early diagnosis. Journal of Biomedical Optics, 26(08). https://doi.org/10.1117/1.jbo.26.8.086007

Mahmood, H., Shaban, M., Indave, B. I., Santos-Silva, A. R., Rajpoot, N., & Khurram, S. A. (2020). Use of artificial intelligence in diagnosis of head and neck precancerous and cancerous lesions: A systematic review. In Oral Oncology (Vol. 110). Elsevier Ltd. https://doi.org/10.1016/j.oraloncology.2020.104885

Marcus, R., & Papaemmanouil, O. (2018, June). Deep reinforcement learning for join order enumeration. In Proceedings of the First International Workshop on Exploiting Artificial Intelligence Techniques for Data Management (pp. 1-4).

Ministério da Saúde. (2020). Instituto Nacional de Câncer José Alencar Gomes da Silva. Estimativa 2020-2022: Incidência de Câncer no Brasil. Rio de Janeiro.

Ravi, D., Wong, C., Lo, B., & Yang, G.-Z. (2016). Deep Learning for Human Activity Recognition: A Resource EfficientImplementation on Low-Power Devices. IEEE Engineering in Medicine and Biology Society. https://doi.org/10.1109/BSN.2016.7516235

Scutti, J. A. B., Pineda, M., Jr, E. E., & Ameida, E. R. de. (2016). Carcinoma de células escamosas de cabeça e pescoço (HNSCC): desvendando os mistérios do microambiente tumoral.

Song, B., Sunny, S., Li, S., Gurushanth, K., Mendonca, P., Mukhia, N., Patrick, S., Gurudath, S., Raghavan, S., Tsusennaro, I., Leivon, S. T., Kolur, T., Shetty, V., Bushan, V. R., Ramesh, R., Peterson, T., Pillai, V., Wilder-Smith, P., Sigamani, A., ... Liang, R. (2021). Bayesian deep learning for reliable oral cancer image classification. Biomedical Optics Express, 12(10), 6422. https://doi.org/10.1364/boe.432365

Uthoff, R. D., Song, B., Sunny, S., Patrick, S., Suresh, A., Kolur, T., Keerthi, G., Spires, O., Anbarani, A., Wilder-Smith, P., Kuriakose, M. A., Birur, P., & Liang, R. (2018). Point-of-care, smartphone-based, dual-modality, dual-view, oral cancer screening device with neural network classification for low-resource communities. PLoS ONE, 13(12). https://doi.org/10.1371/journal.pone.0207493

Welikala, R. A., Remagnino, P., Lim, J. H., Chan, C. S., Rajendran, S., Kallarakkal, T. G., Zain, R. B., Jayasinghe, R. D., Rimal, J., Kerr, A. R., Amtha, R., Patil, K., Tilakaratne, W. M., Gibson, J., Cheong, S. C., & Barman, S. A. (2020). Automated Detection and Classification of Oral Lesions Using Deep Learning for Early Detection of Oral Cancer. IEEE Access, 8, 132677–132693. https://doi.org/10.1109/ACCESS.2020.3010180

Published

2023-07-03

How to Cite

Pereira da Silva, I. A., Rodrigues Rosa de Oliveira, C., dos Santos Oliveira, J. M., Correia Lessa Filho, C. A., & Soares Ferreira, S. M. (2023). Development of a Machine Learning based model for early screening for oral cancer. Diversitas Journal, 8(3), 1488–1493. https://doi.org/10.48017/dj.v8i3.2532