Metformin, Liraglutide and Semaglutide

Antidiabetic drugs used for the purpose of weight loss

Authors

  • Sâmia Moreira de Andrade Centro Universitário Santo Agostinho https://orcid.org/0000-0002-2310-2515
  • Maria Victória Macedo de Andrade Faculdade Facimp Wyden
  • Pedro Henrique Almeida de Faria Faculdade Facimp Wyden https://orcid.org/0009-0002-5799-4117
  • Luís Marcelo Vieira Rosa Federal University of Maranhão
  • Plínio Robson Cavalcante Costa Faculdade Facimp Wyden
  • Luiz Gustavo Freitas Pires Pontifícia Universidade Católica do Paraná

DOI:

https://doi.org/10.48017/dj.v8i4.2720

Keywords:

Diabetes, Obesity, Slimming, Antidiabetic drugs, Rational use of drugs

Abstract

Thepresent study aimed to carry out a bibliographical survey of antidiabetic drugs used for weight loss and their consequences for human health. The drugs most commonly reported in the literature were Metformin, Liraglutide and Semaglutide. The three drugs proved to be effective in weight loss, with Liraglutide having the most pronounced effect, including in clinical studies. Metformin and Semaglutide have been shown to reduce weight, especially when associated with the practice of physical exercise and a change in eating style. However, these drugs have not yet been approved for the purpose of weight loss, and a series of side effects have been reported, mainly associated with the gastrointestinal system, such as nausea, vomiting and diarrhea. Based on the evaluated data, the best way to reduce body weight remains the practice of physical activity and lifestyle changes, and since such practices are not enough, one can opt for the use of anorectics with the proper prescription. and guidance from a health professional. We also highlight the greatest need for the pharmacist, who is responsible for the interface between the drug and the patient, in the education process to avoid the irrational use of antidiabetic drugs in order to lose weight.

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Author Biographies

Sâmia Moreira de Andrade, Centro Universitário Santo Agostinho

Linked to Centro Universitário Santo Agostinho. São Luís, MA, Brazil.

Maria Victória Macedo de Andrade, Faculdade Facimp Wyden

Linked to Faculdade Facimp Wyden. Sítio Novo, MA, Brazil.

Pedro Henrique Almeida de Faria, Faculdade Facimp Wyden

Linked to Faculdade Facimp Wyden. Imperatriz, MA, Brazil.

Luís Marcelo Vieira Rosa, Federal University of Maranhão

Linked to the Federal University of Maranhão (Universidade Federal do Maranhão). São Luís, MA, Brazil.

Plínio Robson Cavalcante Costa, Faculdade Facimp Wyden

Linked to Faculdade Facimp Wyden. Imperatriz, MA, Brazil.

Luiz Gustavo Freitas Pires, Pontifícia Universidade Católica do Paraná

Linked to Pontifícia Universidade Católica do Paraná. Curitiba, PR, Brazil.

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Published

2023-11-02

How to Cite

Andrade, S. M. de, Andrade, M. V. M. de, Faria, P. H. A. de, Rosa, L. M. V., Costa, P. R. C., & Pires, L. G. F. (2023). Metformin, Liraglutide and Semaglutide: Antidiabetic drugs used for the purpose of weight loss. Diversitas Journal, 8(4), 2723–2731. https://doi.org/10.48017/dj.v8i4.2720