Investigação in vitro da atividade antimicrobiana de Mangifera indica frente às bactérias associadas a lesão por pressão
DOI:
https://doi.org/10.48017/Diversitas_Journal-v6i3-1846Abstract
ABSTRACT: Pressure injury they are chronic wounds where the is bacterial infection common and represent a challenging problem for public health. The aim of this study was investigating the antimicrobial activity of Mangifera indica on bacteria associated by pressure injury. In vitro tests were conducted with crude extract and fractions organics against strains Staphylococcus aureus (ATCC 25923), Staphylococcus epidermidis (ATCC 12228), Staphylococcus saprophyticus (ATCC 15305) e Escherichia coli (ATCC 25922) through in agar-well diffusion assay and the minimal inhibitory concentrations (MIC) and minimum bactericidal concentrations (MBC) were determined. The extracts ethanolic was the most active, with diameter of inhibition zones ranging between 19,0 and 22,0 mm against the tested bacterial strains. The CIM varied from 0,04 and 0,29 mg/ml against all the tested microorganism also to the extract ethanolic. The fractions organics hexanic and methanolic showed antimicrobial activity against all the tested microorganisms. Chemical study to extraction and isolation of active compound is recommended to in vitro assays these compounds to investigate the antimicrobial activity.
KEYWORDS: Mangifera indica. Pressure injury. Antimicrobial activity.
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